Sirolimus Eluting
Coronary Stent System


Unmatched XLIMUS
clinical performance.
The ultimate DES for complex artery lesions.

XLIMUS is considered as the ultimate coronary DES stent system to treat complex coronary artery disease by reaching and crossing the most challenging lesions.

News from PCR 2022.
Dr. Luca Testa from Italy presents clinical outcomes of the XLIMIT Trial.
A randomized controlled trial to assess endothelialization.

XLIMUS. Designed for the
most challenging lesions.

  • Optimal Deliverability
  • Optimal Crossability
  • Highest Stenting Success !

XLIMUS DES provides fully biodegradable drug elution.
No stent flaring. No tissue prolapse. Clinically effective.
The unique XLIMUS 6-8-10 stent cell design.

Ensures even vessel wall coverage. Any different artery lesion diameter ranging from 2.25 up to 5.00mm is stented evenly.
Homogenous, clinically effective drug delivery optimizes the anti-proliferative protection of the stented lesion segment.

Homogenous deployment distribution: Surface A1 = A2 = A3

No stent strut flaring. No open gaps.

The technically high standard of 6-8-10 intermediate and closed-cell stent architecture covers all vessel diameters evenly. XLIMUS quality ensures the best possible intracoronary stenting stability and minimizes stenting trauma and restenosis. Extraordinary homogenous vessel wall scaffolding.

XLIMUS assists the cardiologist

with an optimal, unsurpassed tracking performance. It has an innovative Hydrophilic-coated shaft and an extra-low tip profile to access the most tortuous lesions. The ultra-low lesion crossing profile measures only 0.90 mm. The novel XLIMUS Sirolimus-eluting coronary stent system protects the stented lesion segment through extraordinary homogeneous vessel wall scaffolding which minimizes the risk of tissue prolapse and optimizes Sirolimus drug distribution.

XLIMUS drug-coating technology.

A clinically optimized drug-eluting cobalt chromium coronary stent system, which provides clinically effective antiproliferative, abluminal drug delivery to the coronary artery lesion to prevent restenosis, followed by a rapid functional endothelial healing.

  • • Biodegradable Polymer
  • • Sirolimus Drug Elution

Following the nature. Stent flexibility by design.
Controlled biodegradable Sirolimus drug release for
rapid functional endothelial healing.

No signs of vessel toxicity were found. No other safety concerns were noted in animals studied for up to 90 days.

Reliable fully biodegradable Sirolimus drug release
for rapid functional endothelial healing.

The highly biocompatible PLLA (Polylactid acid) drug containing release matrix degrades smoothly and provides an optimal release kinetic profile. Within 30 days, about 70% of the anti-proliferative drug is distributed into the surrounding arterial tissue of the stent struts, ensuring a highly effective inhibition of smooth muscle cell migration and proliferation. Pharmacokinetic study result confirm sustained anti-proliferative drug efficacy up to 120 days.

Cypher 140 µm
Taxus Liberte 97 µm
Endeavor 91 µm
Xience V 81 µm
XLIMUS 71 µm

Thin stent struts minimize foreign body metal volume.

Pulse Synchronous Stent Dynamics respond to coronary artery movement, with every heart beat. Natural stent flexion minimizes friction and shear stress to avoid vessel wall trauma. For a lifetime patient safety! XLIMUS reduces the inflammatory signal potential for prevention of late restenosis.

Source: Peter Smits,MD, from the COMPARE trial presentation at TCT 2009.

Cardionovum clinical program of XLIMUS Sirolimus eluting coronary stent system.

Clinical Program

XLIMUS. The first choice for treating complex coronary artery lesions.

XLIMUS Clinical Performance shows excellent flexibility and pushability for successful Stenting of complex coronary artery lesions. The new XLIMUS DES advances easily through occluded segments when stenting becomes difficult. XLIMUS literature available on request.

Clinical cases
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